For Cervical Dysplasia or Abnormal Pap Smear
Cervical Dysplasia is the abnormal growth of the epithelial tissue on the surface of the cervix.
It refers to a spectrum or continuum of changes specified as: CIN I — mild dysplasia; CIN II — moderate to marked dysplasia; and CIN III — severe dysplasia to carcinoma-in-situ (cancer localized to the intraepithelial tissue/superficial layer of the cervix).
Info Source: (US National Library of Medicine)
CERVAPLEXX I3C is:
Counteracts effect HPV has on estrogen ratio
Proven in double-blind study to reduce degree of HPV-caused cervical dysplasia
Our dosage is the same used in the study
Converts estradiol to weaker metabolites that can be flushed from body
A recent study (MS Word document) done between the Departments of Obstetrics and Gynecology at both the LSU Medical Center-Shreveport and Harvard Medical School and the Strang Cancer Research Laboratory provided convincing evidence that indole-3-carbinol can reverse HPV induced CIN.1
Fifty percent of patients enrolled in a recent study experienced regression from either CIN II or CIN III to Normal in just 12 weeks! (See chart). Further, all patients in the 400mg dosage group regressed to either CIN I or Normal.
|1. placebo||CIN II||CIN I||–||pos||pos|
|2. placebo||CIN II||CIN I||neg||neg||neg|
|3. placebo||CIN II||CIN I||neg||pos||–|
|4. placebo||CIN III||CIN I||neg||pos||–|
|5. placebo||CIN III||CIN I||neg||neg||pos|
|6. placebo||CIN II||CIN I||neg||neg||–|
|7.placebo||CIN II||CIN I||neg||neg||–|
|8. placebo||CIN III||CIN III||neg||pos||–|
|9. placebo||CIN III||CIN I||neg||pos||–|
|10. placebo||CIN III||CIN III||neg||pos||–|
|11. 400||CIN II||CIN I||neg||neg||pos|
|12. 400||CIN II||CIN I||neg||pos||pos|
|13. 400||CIN III||CIN I||neg||pos||–|
|14. 400||CIN II||CIN I||neg||neg||neg|
|15. 400||CIN II||normal||neg||neg||pos|
|16. 400||CIN III||CIN I||neg||pos||pos|
|17. 400||CIN II||normal||neg||neg||pos|
|18. 400||CIN III||normal||neg||neg||pos|
|19. 400||CIN II||normal||neg||pos||–|
|20. 200||CIN III||CIN I||–||pos||pos|
|21. 200||CIN II||normal||neg||pos||–|
|22. 200||CIN III||CIN III||neg||neg||neg|
|23. 200||CIN II||normal||neg||pos||–|
|24. 200||CIN III||normal||pos||pos||–|
|25. 200||CIN II||CIN II||pos||pos||–|
|26. 200||CIN II||normal||neg||neg||pos|
|27. 200||CIN II||CIN II||neg||pos||–|
2Diagnosis by biopsy 3HPV Types 6,11,42,43,44 4HPV Types 16,18,31,33,35,45,51,52,56
List of abbreviations: mg/day – milligrams per day HPV– human papillomavirus CIN – cervical intraepithelial neoplastia PCR – polymerase chain reaction neg – negative pos – positive
The basis for this study was indole-3-carbinol’s efficacy against laryngeal papillomas that are typically caused by HPV strains 6 and 11. These are the same strains that cause genital warts; therefore, it may be hypothesized that the indole-3-carbinol would also be effective against genital warts.
The proposed mechanism of indole-3-carbinol resides in its ability to convert estradiol to 2-OH-estrone rather than the potentially carcinogenic 16a-OH-estrone. It is believed that HPV alters the estrogen ratio toward 16a-OH-estrone. The indole-3-carbinol reverses this trend.
Cervaplexx I3C™ (30 capsules is one month’s supply) is now available without a prescription in 400mg capsules. It contains pure indole-3-carbinol, a natural substance found in cruciferous vegetables (400mg = about 1/3 head of cabbage). There is no noted toxicity.
1Bell, M.C., Crowley-Nowick, P., Bradlow, H.L., et al., 1999, “Indole-3-carbinol in the treatment of CIN”, Society of Gynecologic Oncologists, San Francisco, CA.
WE RECOMMEND A 12 WEEK (3 BOTTLE) DOSAGE PERIOD TO EVALUATE HOW EFFECTIVE CERVAPLEXX I3C WILL BE FOR YOU, AS THIS WAS THE TIME FRAME OF THE STUDY. ACCORDINGLY, WE ARE NOW OFFERING A 3 BOTTLE TRIAL/REFILL PACK (BUY 2 BOTTLES & GET 1 BOTTLE FREE) FOR BOTH NEW AND EXISTING CUSTOMERS.
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